I assume you are running it in Windows. If so, then I also assume you did not read the attached README
D0xBase cannot run on Windows by itself. Because it uses Curses lib, which is a Linux/Unix thing, it can be ran in such an environment. On Windows you can do it in Cygwin.
Of course if you are not on windows, then more info is needed, like the error that you get. We usualy need last 10-15 lines of the error.
It is also meant to be opened from the Terminal, running with Python.
In general, just read the attached README - everything is explained there.
