Well look at the equation that he obtained. Luckily he is able to divide the fraction in such a way so that you have only multiplications, which alleviates the biggest problem (in the future you won't be able to do that anymore: polynomial functions etc).
Your fraction is (2x-5)(x+2)/(4-x)(3+x) > 0
x cannot be 4 or -3 otherwise the fraction doesn't make sense (DIVIDE BY ZERO BRAH!)
You ask why the start with a minus, so let's see the reasoning:
assume x = -4;
input into equation => [2*(-4)-5]*[(-4)+2]/[4-(-4)]*[3+(-4)] > 0 => (-8-5)*(-4+2)/(4+4)*(3-4) > 0
=> -13*(-2)/8*(-1) > 0 => 26/-8 > 0 False;
Because the result doesn't make mathematical sense, and you want it to (the solution is always in the "+" intervals), it means that you can't find a root in the specific interval, which in this case is [-infinity;-3).
Now since solution intervals are positive, non-solution intervals must be negative, and (-infinity;-3] has no value which correctly solves the inequation.
As Deque correctly said, it's sometimes difficult to translate mathematical concepts from mother-tongue to English, but I hope you get what I mean.