Been using Avast for 2 years now, nice and simple interface and keeps my windows secure.
this is because you've always downloaded stuff from Trustful websites, Avast is the most silliest Antivirus, it is very much easier to bypass.
In my view Panda Antivirus is the best because it doesn't even allow the process 'wscript.exe' to be run while Avast don't even bother to see what is happening inside the VBScript code